Excitement builds for long-acting TB treatments, but research still at early stage

Excitement builds for long-acting TB treatments, but research still at early stage

Both TB treatment and TB preventive therapy involve taking lots of pills, usually for several months. Researchers are working on new long-acting formulations that might, for example, reduce an entire course of TB preventive therapy to a single injection. Catherine Tomlinson reports.

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Yogan Pillay and Gaurang Tanna | Commit, invest, deliver: What should SA do to end TB?

Yogan Pillay and Gaurang Tanna | Commit, invest, deliver: What should SA do to end TB?

The TB Sustainable Development Goals of reducing incidence and deaths from TB are achievable, if we all work together. We must double down on this ambition and be even bolder in our investments, write Yogan Pillay and Gaurang Tanna.

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Fears grow for R800 million cut to US funding of medical research in SA

Fears grow for R800 million cut to US funding of medical research in SA

Medical researchers in South Africa are in limbo as they wait to hear whether over R800 million in research grants from the United States National Institutes of Health will be terminated. South Africa’s top universities, which receive the bulk of the funding, will be particularly hard hit if the cuts materialise. Catherine Tomlinson reports.

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A jab that could protect against HIV for a year at a time, and other highlights from major conference

A jab that could protect against HIV for a year at a time, and other highlights from major conference

A single shot of a new formulation of the antiretroviral drug lenacapavir could potentially provide protection against HIV infection for as long as a year. Elri Voigt reports on this and some of the other exciting research on long-acting anti-HIV medicines presented at the Conference on Retroviruses and Opportunistic Infections.

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“We’ll come to you”: HIV prevention project takes services to schools

“We’ll come to you”: HIV prevention project takes services to schools

Elzette Rousseau from the Desmond Tutu HIV Foundation told attendees at the top HIV conference in The United States about a project taking HIV prevention services to schools in Cape Town. Biénne Huisman visited one of the sites to find out how it works.

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In-depth | How much does our HIV response depend on US funding?

In-depth | How much does our HIV response depend on US funding?

After the US slashed global aid, the South African government stated that only 17% of its HIV spending relied on US funding. But some experts argue that US health initiatives had more bang for buck than the government’s programmes. Jesse Copelyn looks past the 17% figure, and considers how the health system is being affected by the loss of US money.

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US funding cuts imperil search for HIV vaccine

US funding cuts imperil search for HIV vaccine

A groundbreaking project to study potential HIV vaccines in several African countries has been derailed by an abrupt cut in funding from the United States government. As a result, several promising vaccine candidates might not be tested in clinical trials. Catherine Tomlinson reports.

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SA unveils ambitious new HIV campaign amid aid crisis

SA unveils ambitious new HIV campaign amid aid crisis

Amid major disruptions caused by aid cuts from the United States government, the health department aims to enrol a record number – an additional 1.1 million – of people living with HIV on life-saving antiretroviral medicine this year. Experts tell Spotlight it can’t be business as usual if this ambitious programme is to have a chance of succeeding. Ufrieda Ho reports.

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Massive $200 million TB research programme derailed by US funding cuts

Massive $200 million TB research programme derailed by US funding cuts

Just over a month after US President Donald Trump implemented a 90-day freeze of all foreign assistance, the future looks very uncertain for tuberculosis research. Among others, a large TB research programme that was worth up to $200 million was axed last week. Elri Voigt reports.

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Francois Venter | Our HIV response will collapse without US funding – unless we act urgently

Francois Venter | Our HIV response will collapse without US funding – unless we act urgently

South Africa faces its worst health crisis in 20 years. Worse than COVID, and one that will overshadow diabetes as a major killer, while pouring petrol on a dwindling TB fire. But it is preventable, argues Professor Francois Venter if our government steps up urgently.

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USAID funding cuts end vital HIV programme for orphans

USAID funding cuts end vital HIV programme for orphans

South Africa’s public health system is in turmoil after the widespread cancellation of USAID funding agreements. Among others, a USAID-funded project that helped to keep orphaned children on their HIV medication was forced to close. HIV testing services are also severely impacted in some areas.

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Research hub aims to decode health challenges facing ‘people of the dew’

Research hub aims to decode health challenges facing ‘people of the dew’

A new health research hub brings hope of improving health services in the Rustenburg Valley in the North West Province. Nthusang Lefafa finds out more about how the Bafokeng Health and Demographic Surveillance System Node will work and what it has to offer.

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